Pharmaceutical Spray Drying Market is estimated to value over USD 4 billion by 2028 end with a CAGR of over 7% during the forecast period 2021 to 2028. Spray drying is one of the most promising pharmaceutical technologies presently available. The process is continuous and converts a liquid into a powder in a single step and is ideal when precise attributes are required, such as particle size, morphology, and stability. In this review, we describe the technology, current and future applications, and how current understanding and modeling tools facilitate a risk-free, lean process development stage.